I guess there are tradeoffs?
SEO onwards- i did hear it will be hard for you to try to apply to HQ postings, because many deputy directors, assistant directors or senior assistant directors are at SEO and above level.
Usually SEO positions in HQ will be for these positions which they usually may have earmarked certain people for the positions already (eg scholars)

Work-life balance- not sure if it makes a difference coz it’s about the job scope and duties u still need to fulfill in that portfolio.